Toxicity and teratogenicity in zebrafish Danio rerio embryos exposed to chromium

Chromium (Cr) is an element present in nature mineral form. It has a dual effect, both as essential micronutrient and carcinogenic agent depending on its chemical form concentration. various environmental matrices such water, soil, air, coming from natural anthropogenic sources, causes harmful effects biota, ecosystems, even human beings. This study's objective was to evaluate chromium toxicity teratogenicity zebrafish embryos of Danio rerio exposed through the D. teratology assay (DarTA) test by evaluating spine malformations. To this end, curve calculated potassium dichromate (K2Cr2O7), probit used establish mean lethal concentration (LC50) three subtoxic concentrations LC25, LC12.5, LC6.25 teratogenicity. The results showed that statistically positive for teratogenic effect at highest evaluated. Potassium exposure abnormal embryonic development effects, including severe heart defects embryos. Therefore, we conclude toxic developmental stages. finding suggests metal should be tested potential risk mammalian systems.